DIABETIC PERIPHERAL NEUROPATHY (DPN)
Diabetic neuropathies are among the most common complications of diabetes, affecting over 50% of diabetic individuals. DPN results in the degeneration of nerve cells in the eyes and bodily extremities (such as hands and feet), causing pain, numbness, loss of sensation and overall decreased quality of life. Currently, there is no known treatment to prevent the onset or progression of diabetic neuropathy.
AUUM's specific formulation was the subject of a Canadian Diabetes Association funded clinical trial investigating whether 12-months of seal oil supplementation could stop the progression of diabetic neuropathy in individuals with Type 1 diabetes. The results found that on average patients on average experienced a 29% increase in corneal nerve fibre length when supplementing AUUM oil, which is considered to be representative of small nerve fibre regeneration in other parts of the body.
- Evan J.H. Lewis, Bruce A. Perkins, Leif E. Lovblom, Richard P. Bazinet, Thomas M.S. Wolever, Vera Bril. Effect of omega-3 supplementation on neuropathy in type 1 diabetes. Neurology, 2017; 88 (24): 2294 DOI: 10.1212/WNL.0000000000004033
CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (CIPN)
Much like DPN, neuropathies resulting from nerve damage caused by chemotherapy treatment used by cancer patients remain a major problem. The same pain, numbness, loss of sensation and overall decreased quality of life is present for victims of CIPN, and once again, there is currently no known treatment to prevent the onset or progression of chemotherapy induced peripheral neuropathy.
AUUM is currently working with researchers at the McGill University Health Centre on a clinical trial investigating the use of AUUM Sublingual-D for the treatment of CIPN. Preliminary results are very positive, showing a clear benefit to taking AUUM's Sublingual-D formulation, though the full results of the study will be released later in 2017.
AUUM's principal goal is to help create happier, healthier and better performing individuals. Athletes can win or lose based on the efficiency of their nerves. The ability of skeletal muscles to generate force and resist fatigue is essential to sport performance. All muscle contractions result from nerve signals and therefore superior nerve-muscle interaction translates to increased performance. Researchers at the University of Toronto conducted a study on well-trained athletes, and demonstrated that AUUM's Sublingual-D formulation both increased muscle activation (by 9%) and reduced fatigue (by 5%).
- Evan J.H. Lewis, Peter W. Radonic, Thomas M. S. Wolever, Greg D. Wells. 21 days of mammalian omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes compared to olive oil placebo. Journal of the International Society of Sports Nutrition, 2015; 12 (28) DOI: 10.1186/s12970-015-0089-4
The brain requires essential omega-3 fatty acids for proper development and function. Many studies demonstrate a clear link between omega-3 intake and mood, depression, anxiety and optimal cognitive function. In children with mental health challenges, AUUM Sublingual-D was shown to dramatically improve communication, aggression, moodiness/frustration and participation at school.